Septerna ($SEPN) Insider Trading & Smart Money Activity

Septerna, Inc. · Biotechnology · Latest filing Jul 1, 2026

Septerna, Inc. ($SEPN) has 8 insider trades, 2 13F position changes and 3 analyst ratings on file. Insiders filed 8 Form 4 transactions in the last 12 months, none of them open-market purchases or sales.

Insider buyers (12 mo)
0
Insider sellers (12 mo)
0
Net insider $ (12 mo)
$0
Congress trades (12 mo)
0
13F moves on file
2
Analyst ratings on file
3

SEPN insider buying and selling by quarter

QuarterInsider buysInsider salesCongress buys / sales13F added / cut
Q1 2026 0 0 0 / 0 0 / 0
Q2 2026 0 0 0 / 0 0 / 2
Q3 2026 0 0 0 / 0 0 / 0
Q4 2026 0 0 0 / 0 0 / 0

Insider buys and sales count open-market trades only (Form 4 codes P and S). Grants, option exercises and tax withholding are left out.

All SEPN insider, congress, 13F and analyst activity

DateSourceWhoActionSharesValue / amount ΔOwn1W1M6MFilingStory
Analyst Truist Securities Reiterates to buy PT $43 +5.2%-0.5% Read
Analyst HC Wainwright Reiterates to buy PT $40 +5.2%-0.5% Read
Analyst Guggenheim Reiterates to buy PT $45 +5.2%-0.5% Read
Insider Samira ShaikhlyChief People Officer Sell (Option exercise) 2.18K sh -3.7%-3.3% —
Insider Samira ShaikhlyChief People Officer Buy (Option exercise) 2.18K sh $14.83K -3.7%-3.3% —
Insider Shalini Sharp Buy (Grant or award) 15K sh -10.4%-10.3% Read
Insider L.P. Ra Capital Management Buy (Grant or award) 15K sh -10.4%-10.3% Read
Insider Alan Ezekowitz Buy (Grant or award) 15K sh -10.4%-10.3% Read
Insider Bernard Coulie Buy (Grant or award) 15K sh -10.4%-10.3% Read
Insider Daniel LongSVP, Drug Discovery Sell (Option exercise) 15K sh -0.3%-1.9% —
Insider Daniel LongSVP, Drug Discovery Buy (Option exercise) 15K sh $81.37K -0.3%-1.9% —
13F Driehaus Capital Management Reduced -413.90K sh $147.21M +5.2%+33.7% Read
13F Driehaus Capital Management Reduced -413.90K sh $150.06M +5.2%+33.7% Read

1W / 1M / 6M = how SEPN moved from the trade or filing date.

Insider trading in SEPN: who is buying and selling

InsiderRoleTradesOpen-market netShares heldLast trade
Samira Shaikhly Chief People Officer 2 — Jun 29, 2026
Shalini Sharp 1 — Jun 26, 2026
L.P. Ra Capital Management 1 — Jun 26, 2026
Alan Ezekowitz 1 — Jun 26, 2026
Bernard Coulie 1 — Jun 26, 2026
Daniel Long SVP, Drug Discovery 2 — Jun 22, 2026

Institutions moving SEPN (13F)

Analyst ratings on SEPN

DateFirmActionRatingPrice target1W1M6MStory
Truist Securities Reiterates buy $43 +5.2%-0.5% Read
HC Wainwright Reiterates buy $40 +5.2%-0.5% Read
Guggenheim Reiterates buy $45 +5.2%-0.5% Read

Frequently asked questions

What is the latest insider trade in SEPN?

Samira Shaikhly, Chief People Officer filed a sell (option exercise) of 2.18K sh on Jun 29, 2026.

Which institutions changed their SEPN positions?

Recent 13F filers moving the stock include Driehaus Capital Management.

Other biotechnology stocks

Data comes from public SEC Form 4 and 13F filings and STOCK Act disclosures. Dates are the trade or filing date reported. This page is for research only and is not investment advice.

Get trade alerts by text