Spero Therapeutics (SPRO) Insider Tregoning Buys 10,000 Shares

Kathleen Tregoning acquired 10,000 shares of SPRO on June 23, 2026.

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Kathleen Tregoning bought 10,000 shares of Spero Therapeutics, Inc. ($SPRO) on June 23, 2026. The trade was reported to the SEC in a Form 4 filing.

Since the trade, $SPRO is up 2.8% after 1 week, down 46.0% after 1 month and down 48.8% to date (from the $2.15 close on Jun 23, 2026).

Find the original: SPRO Form 4 filings on SEC EDGAR

SPRO Spero Therapeutics, Inc.
$1.10 -53.19% year to date
Daily close · Oct 16, 2026

Key Points

  • Kathleen Tregoning bought 10,000 shares of SPRO on June 23, 2026.
  • SPRO traded at $2.02 on Friday with no significant P/E ratio.
  • Vanguard Capital Management opened a new position in SPRO with 1,799,880 shares.

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Kathleen Tregoning purchased 10,000 shares of SPRO on June 23, 2026. The transaction was not pre-planned and comes as part of a series of insider buys on the same day.

Insider Buying and Selling at Spero Therapeutics, Inc.

Several insiders at SPRO made significant purchases on June 23, 2026. Jackson Scott Thomas, John Pottage Jr, Milind Deshpande, Cynthia Smith, Patrick V.J.J. Vink, and Frank Thomas each bought shares ranging from 10,000 to 20,000. These transactions were not part of any pre-arranged trading plans.

Other Institutional Activity in SPRO

Vanguard Capital Management LLC opened a new position in SPRO, acquiring 1,799,880 shares valued at approximately $4.21 million. Renaissance Technologies LLC reduced its holdings by 90,287 shares, leaving it with 1,189,235 shares worth about $2.78 million, marking a 7.1% decrease. Two Sigma Investments, LP significantly increased its stake by 513,061 shares, now holding 885,631 shares valued at $2.07 million, representing a 137.7% increase.

Spero Therapeutics, Inc. Stock Up 78.8%

Shares of SPRO traded at $2.02 on Friday. The stock does not currently have a meaningful P/E ratio as it is not profitable. SPRO's market performance includes a 52-week low of $1.50 and a high of $3.50. The stock's 50-day moving average is $2.10, while the 200-day moving average stands at $2.30.

Analysts Set New Price Targets

On January 30, 2025, HC Wainwright & Co. reiterated its buy rating for SPRO with a price target of $5.00. Evercore ISI Group downgraded the stock to hold with the same target price on December 20, 2024. Previously, HC Wainwright & Co. had reiterated its buy rating multiple times, with targets ranging from $5.00 to $7.00.

Bottom Line

Kathleen Tregoning's purchase of SPRO shares adds to a series of insider buys, indicating confidence in the company's prospects. Investors often track insider transactions for potential insights, although these filings are backward-looking and may not reflect current positions. Institutional activity and analyst ratings provide additional context for SPRO's market standing.

Source: Kathleen Tregoning's Form 4 filing on $SPRO (Jun 23, 2026). Find the original filing: SPRO Form 4 filings on SEC EDGAR. Written by software, not financial advice. How we make alerts

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