Upstream Bio ($UPB) Insider Trading & Smart Money Activity

Upstream Bio, Inc. · Biotechnology · Latest filing Jun 16, 2026

Upstream Bio, Inc. ($UPB) has 5 insider trades and 2 analyst ratings on file. In the last 12 months on the open market, no insider bought and 5 insiders sold ($30.62K), net -$30.62K.

Insider buyers (12 mo)
0
Insider sellers (12 mo)
5
Net insider $ (12 mo)
-$30.62K
Congress trades (12 mo)
0
13F moves on file
0
Analyst ratings on file
2

UPB insider buying and selling by quarter

QuarterInsider buysInsider salesCongress buys / sales13F added / cut
Q1 2026 0 0 0 / 0 0 / 0
Q2 2026 0 5 · $30.62K 0 / 0 0 / 0
Q3 2026 0 0 0 / 0 0 / 0
Q4 2026 0 0 0 / 0 0 / 0

Insider buys and sales count open-market trades only (Form 4 codes P and S). Grants, option exercises and tax withholding are left out.

All UPB insider, congress, 13F and analyst activity

DateSourceWhoActionSharesValue / amount ΔOwn1W1M6MFilingStory
Insider Sutherland Everett RandChief Executive Officer Sell (Open-market sale) 2.10K sh $12.78K +6.8%+22.1% —
Insider Adam HoughtonChief Business Officer Sell (Open-market sale) 700 sh $4.27K +6.8%+22.1% —
Insider Michael GrayCFO and COO Sell (Open-market sale) 853 sh $5.20K +6.8%+22.1% —
Insider Aaron DeykinChief Medical Officer Sell (Open-market sale) 895 sh $5.46K +6.8%+22.1% —
Insider Allison AmbroseGeneral Counsel Sell (Open-market sale) 477 sh $2.91K +6.8%+22.1% —
Analyst JP Morgan Lowers to hold PT $8 +3.3%+19.3% Read
Analyst JP Morgan Lowers to hold PT $8 +3.3%+19.3% Read

1W / 1M / 6M = how UPB moved from the trade or filing date.

Insider trading in UPB: who is buying and selling

InsiderRoleTradesOpen-market netShares heldLast trade
Sutherland Everett Rand Chief Executive Officer 1 -$12.78K Jun 16, 2026
Adam Houghton Chief Business Officer 1 -$4.27K Jun 16, 2026
Michael Gray CFO and COO 1 -$5.20K Jun 16, 2026
Aaron Deykin Chief Medical Officer 1 -$5.46K Jun 16, 2026
Allison Ambrose General Counsel 1 -$2.91K Jun 16, 2026

Analyst ratings on UPB

DateFirmActionRatingPrice target1W1M6MStory
JP Morgan Lowers hold $8 +3.3%+19.3% Read
JP Morgan Lowers hold $8 +3.3%+19.3% Read

Frequently asked questions

Are UPB insiders buying or selling?

Over the last 12 months 0 insiders made 0 open-market purchases worth $0 and 5 insiders made 5 open-market sales worth $30.62K, a net -$30.62K.

What is the latest insider trade in UPB?

Sutherland Everett Rand, Chief Executive Officer filed a sell (open-market sale) of 2.10K sh worth $12.78K on Jun 16, 2026.

Other biotechnology stocks

Data comes from public SEC Form 4 and 13F filings and STOCK Act disclosures. Dates are the trade or filing date reported. This page is for research only and is not investment advice.

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